Centre for Applied Health Research

PERFORM (Personalised Exercise-Rehabilitation for People with Multiple Long-Term Conditions (Multimorbidity) Trial

The PERFORM (Personalised Exercise-Rehabilitation For people with Multiple long-term conditions (multimorbidity)) trial has been awarded funding from the National Institute for Health Research (NIHR) Programme Grants to co-develop (with patients, caregivers, clinicians, and service commissioners) a bespoke programme of personalised exercise-based rehabilitation for people with multimorbidity and to evaluate its acceptability, clinical effectiveness, and cost-effectiveness of its implementation into the NHS.

Research has shown that exercise-based rehabilitation can improve quality of life and reduce the number of hospital visits. Standard NHS rehabilitation can help people with specific illnesses such as heart disease or respiratory problems. But it is increasingly recognised that such rehabilitation programmes do not meet the needs the increasing number of people presenting with long-term conditions.

Work Packages include:

  • Work Package 1 : Identifying people with multiple Long Term Conditions (LTCs) likely to benefit from rehabilitation
  • Work Package 2: Intervention development
  • Work Package 3: Feasibility trial with embedded process and economic evaluation
  • Work Package 4: Multicentre randomised controlled trial and prospective cohort study
  • Work Package 5: Role of Social Media (SoMe) networks are widespread in the course of daily life, some shown to foster positive health behaviour (Lead by University of Salford)

Funder:

National Institute for Health Research (NIHR) Programme Grant

Team  

University of Saford Work Package 5 Leads:  

Professor Paula Ormandy, University of Salford

Dr Cristina Vasilica, University of Salford

Principal investigators:

Professor Sally Singh, University of Leicester

Professor Rod Taylor, Glasgow University

Co-investigators:

Dr Shaun Barber, University of Leicester

Gwen Barwell, University of Leicester

Professor Sarah Dean, University of Exeter

Professor Patrick Doherty, University of York

Dr Rachael Evans, University of Leicester

Nikki Gardiner, University Hospitals of Leicester

Professor Colin Greaves, University of Birmingham

Dr Tracy Ibbotson, Glasgow University

Dr Bhautesh Jani, Glasgow University

Professor Kate Jolly, University of Birmingham

Professor Frances Mair, Glasgow University

Professor Emma McIntosh, Glasgow University

Professor Paula Ormandy, University of Salford

Professor Sharon Simpson, Glasgow University

Dr Susan Smith, Dublin University

Publications:

Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions – PERFORM: protocol for a randomised feasibility trial, Sharon Anne Simpson, Rachael A Evans, Hannah Rosemary Gilbert , Amy Branson, Shaun Barber, Emma McIntosh, Zahira Ahmed, Sarah Gerard Dean , Patrick Joseph Doherty , Nikki Gardiner, Colin Greaves, Paulina Daw, Tracy Ibbotson, Bhautesh Jani, Kate Jolly , Frances Mair , Paula Ormandy, Susan Smith, Sally J Singh, Rod Taylor, BMJ Open, April 05, 2024 10.1136/bmjopen-2023-083255

Evidence for exercise-based interventions across 45 different long-term conditions: an overview of systematic reviews, Grace O. Dibben, Lucy Gardiner, Hannah M. L. Young, Valerie Wells, Rachael A. Evans, Zahira Ahmed, Shaun Barber, Sarah Dean, Patrick Doherty, Nikki Gardiner, Colin Greaves, Tracy Ibbotson, Bhautesh D. Jani, Kate Jolly, Frances S. Mair, Emma McIntosh, Paula Ormandy, Sharon A. Simpson, Sayem Ahmed, Stefanie J. Krauth, Lewis Steell, Sally J. Singh, Rod S. Taylor, on behalf of the PERFORM research team, eClinicalMedicine, April 30, 2024 10.1016/j.eclinm.2024.102599

Partners:

Glasgow University

Dublin University

University of Birmingham

University of Exeter

University of York

University of Leicester

University Hospitals of Leicester